Male infertility is one of the world’s best-kept secrets. More than half of the world’s cases of involuntary childlessness are caused by male infertility, and in the Middle East, the rates are much higher. Male infertility clusters in Middle Eastern families, is hereditary in nature, and likely linked to widespread practices of cousin marriage. Yet, the “secret” of male infertility generally unfolds only in in vitro fertilization (IVF) clinics, where many Middle Eastern men are engaged in high-tech forms of assisted reproduction. Through in-depth ethnography undertaken in assisted reproductive technology (ART) clinics in four countries, this paper captures the marital, moral, and material commitments of infertile Middle Eastern men as they engage with ARTs. Emerging technologies—particularly intracytoplasmic sperm injection (ICSI) to overcome male infertility—are changing Middle Eastern men’s lives and moral subjectivities. In particular, when men are asked to masturbate “on demand” as part of assisted reproduction regimes, some Muslim men bring their moral anxieties about masturbation with them, and are therefore unable to produce critically important semen samples. In these cases, painful sperm aspirations directly from the testicles are often required. Having said this, men’s masturbation is now accepted as a routine part of assisted reproduction in the Middle East, and is one of many practices signifying men’s “emergent masculinities,” or newly embodied ways of being men. Although masturbation may be viewed as zina in Islam, millions of Muslim men are masturbating out of medical necessity, and some are even embracing the idea of masturbation as a healthy, pleasurable, and guilt-free form of male sexuality. Indeed, in today’s Middle East, men are rethinking their emergent masculinities as they undertake masturbation and assisted conception out of devotion to the wives they love. With the “coming out” of men’s fertility and sexuality secrets in IVF clinics across the region, this paper questions taken-for-granted assumptions about Middle Eastern men as men in an era of emerging science and technology. ?????