While the covid-19 pandemic has centered attention on uncertainty, which is currently being experienced in more profound ways on a global scale, uncertainty has been a common feature of life in the oPt. Uncertainty in the oPt impacts various life dimensions and is marked by chronicity, and is shaped by ongoing settler-colonialism. However, in the social science and health literatures, uncertainty is oftentimes conceptualized as a more acute or temporary phenomenon, whether experienced during the course of illness or acute shocks. Uncertainty is less often conceptualized as structural or intrinsically chronic, but rather as a passing event or temporary experience. This shortcoming in the conceptualization of uncertainty itself calls into question the relevance of salient concepts to contexts where uncertainty is chronic and widespread, including the Palestinian context. Our research, beginning in September 2019, set out to explore people’s conceptualizations and lived experiences of uncertainty in the oPt. Building on over a year-and-a-half of research, which included over seventy in-depth interviews, we explore conceptions and Palestinians’ experiences of uncertainty throughout the West Bank before and during the covid-19 pandemic. We seek to understand how new uncertainties produced by the pandemic are experienced and understood within a context of chronic uncertainty. Do people understand this experience as being distinctive? How do past experiences with chronic uncertainties inform modalities of dealing with uncertainties in the present pandemic moment? We find that experiences of uncertainty are multilayered, stemming from the political context and permeating through various dimensions of life, including economic uncertainty, safety and security, and aspects of social life. We find that class, place, gender, and age (or life phase) shape people’s experiences of uncertainty, especially in more marginalized communities, where uncertainty is simultaneously chronic and acute. The pandemic added new forms of the ‘unknown’ as some interlocutors put it, which also interacted with preexisting uncertainties, especially in the Jordan Valley communities facing the threat of de jure annexation alongside the pandemic. Our interlocutors navigated uncertainty in various ways, at times constricting the physical and social spaces they interact with in order to reduce their exposures to acute uncertainties, often linked to the potential for mobility. They create alternatives and amidst the uncertainty and chaos of the everyday find ways and create new possibilities.